The diagram depicts the anatomical and pathological features underlying the Carey Coombs murmur, highlighting a heart with rheumatic mitral valvulitis. It shows the left atrium, left ventricle, mitral valve leaflets that are thickened and inflamed, chordae tendineae, and papillary muscles. Arrows indicate turbulent blood flow across the thickened mitral valve leaflets into the left ventricle. A waveform illustrates the heart sounds S1, S2, and the delayed diastolic murmur characteristic of Carey Coombs murmur. A text box lists the five steps in the mechanism: acute rheumatic fever causing valvulitis, edema and thickening of leaflets, transient valve obstruction, turbulent flow, and resultant low-pitched mid-diastolic rumble. Icons compare a normal valve and one with valvulitis.